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Recombinant human purine nucleoside phosphorylase (PNP) with a histidine tag supplied as a purified protein for laboratory research. The protein is intended for enzymology, biochemical assays, structural studies, and related experimental applications where a human PNP reagent is required.
Recombinant human PNP with a His tag.
Supplied as purified protein for research use.
Suitable for enzymatic assays and activity studies.
Useful for structural biology and protein-ligand interaction experiments.
Available in small research sizes such as 50 μg.
Provided with product documentation such as datasheet or certificate of analysis.
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5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. It can be used to replace unmodified mRNA, which leads to an increase in translational properties and stability, and a reduction in innate immune responses in human and other mammalian cells.
Increases translational properties
Enhances stability of mRNA
Reduces innate immune responses in mammalian cells
For research use only
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Medchemexpress, HY-W009444 1g 5-Methyluridine CAS:1463-10-1 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress, HY-W011527 50mg Xanthosine CAS:146-80-5 Xanthosine is a nucleoside derived from xanthine and ribose. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. It is composed of a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). The antitumor activity primarily stems from its inhibition of thymidylate synthase (TS) and its incorporation into DNA.
Potent and orally active nucleoside antitumor agent
Composed of a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI)
Inhibits thymidylate synthase (TS)
Incorporates into DNA for antitumor activity
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A purine nucleoside analog; reduces infection of Calu-3 cells by SARS-CoV-2 (EC50 = 0.04 µM) but is also toxic to Calu-3 cells (CC50 = 1.14 µM); decreases tumor volume and increases the number of tumor cells with telomere dysfunction-induced foci in an A549 NSCLC mouse xenograft model at 2 mg/kg; increases the number of PD-1+ CD8+ T cells, as well as induces tumor regression when administered in combination with anti-PD-L1 in MC-38 murine colon carcinoma models
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5-fluorocytidine is a fluorinated cytidine nucleoside that inhibits maturation of the 45S ribosomal RNA precursor and is provided as a characterized research reagent with storage and safety guidance from product datasheets and SDS.
Fluorinated cytidine nucleoside.
Inhibits maturation of the 45S ribosomal RNA precursor.
Molecular formula C9H12FN3O5.
Molecular weight 261.21 g/mol.
Storage: 4°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
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